Source Omega LLC
Source Omega
Chapel Hill, NC 27516
Phone: 919-360-5275
Email info@source-omega.com
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Source-Omega Reviews DHA Retroconversion Metabolic Dosing Using Algae Oil Omega-3s as a Fish Oil Substitute November, 2010

"What all the human omega-3 red blood cell data independently points out is that DHA is always 3 to 8 fold more abundant than EPA in human blood and tissues, even after prolonged intake of high doses of omega-3s predominantly as EPA," says company scientist.

Source-Omega Reviews DHA Retroconversion Metabolic Dosing Using Algae Oil Omega-3s as a Fish Oil Substitute
Chapel Hill, NC, November 10, 2010 --(PR.com)-- Today, Source-Omega revealed knowledge gained from their review of the omega-3 literature and published research. “What all the human omega-3 Red Blood Cell data independently point out is that DHA is always 3 to 8 fold more abundant than EPA in human blood and tissues, even after prolonged intake of high doses of omega-3s predominantly as EPA," says Scott Doughman, PhD., Chief Scientist at Source-Omega.

Source-Omega revealed their discussion, forwarding that composition studies in 1978 proved DHA is naturally the most abundant omega-3 form in the human body and blood in comparison to EPA levels in untreated individuals (Sanders et al., 1978). In 1986, a review by Herold and Kinsella of human volunteers treated with fish oil omega-3s revealed higher DHA fatty acid composition in red blood cells compared to EPA, despite high EPA intake (Herold and Kinsella, 1986).

Fish oils have been an abundant source of EPA, so fewer studies may have taken into consideration that DHA is the most abundant omega-3 long chain fatty acid because EPA was the main omega-3 given as a fish oil treatment.

When Conquer and Holub published on algae oil DHA treatment of human subjects in 1996, a detailed double-blind randomized placebo controlled study, the authors found blood omega-3 parameters consistent with humans taking high dosages of fish oil (Conquer and Holub, 1996). The 1996 study showed RBC increases in both DHA and EPA through accretion of DHA and retroconversion of DHA. Other metabolism studies have shown DHA is also a template that will provide all the C22, C20, and C18 omega-3s needed in the body through retroconversion, say Source-Omega scientists.

DHA delivers saturation levels of omega-3s to RBC membranes when the DHA dosage for adult clinical use begins with 1.0 g to 1.2 g DHA per day, which company results, or previous published studies show can provide saturation levels of omega-3s within 90 days (Arterburn et al., 2008).

The scientific literature shows high-dose DHA derived from microalgae lowers hypertriglyceridemia after 90 days of treatment, by up to 26 percent with at least 1 g DHA daily (reviewed by Ryan et al., 2009). With a safe, effective dosage range for any adult, the GRAS safety registration of algae oil and the dosage range have been positively ruled-upon, as such, by several international regulatory bodies.

"The summary of these historical studies together suggest 'directional omega-3 metabolism', where fish oil is 'uphill' and algae oil is 'downhill'. EPA intake leads to multistep synthesis to DHA with fish oil. DHA intake leads to a single step retroconversion to EPA with algae oil. The body knows how to balance its final levels from each direction, but 'downhill' appears more efficient at high omega-3 doses," said Doughman.

Each method then flows towards a somewhat pre-defined homeostatic balance of cellular and tissue specific omega-3 compositions, the data suggest.

Since the DHA retroconvertion dosing strategy is the opposite of fish oil, Source-Omega's patent pending claims are on the dosage use and method of 1200 mg DHA + 40 mg EPA per day as metabolically ideal for certain health claims and postprandial triglyceride lowering benefits [References Available upon request from Source-Omega].

About Source-Omega: Source-Omega, LLC is headquartered in Chapel Hill, North Carolina, near the Research Triangle Park. It was founded in 2007 and specializes in the international marketplace for manufacturing, branding, private labeling and globalization of algae oil nutritional products under the name and formula Pure One™, the Next Generation Plant Based Omega-3™ for their Omega-3 DHA Therapy™, for clinics offering triglyceride lowering plasma lipids management programs and for pregnancy, nursing and family care.


Source-Omega’s Pure One Untouched by Seawater Pollution, Not Now, Not Ever July, 2010

For years, the lack of fish odor or reflux taste has led many people to microalgae oil instead of fish oil as a source for omega-3s. Another feature of microalgae oil is now more important than ever — it is not touched by any ocean, now or ever.

Chapel Hill, NC, July 07, 2010 --(PR.com)-- Pure-One™, manufactured by North Carolina-based Source-Omega, is actually the same DHA-rich algae oil eaten by ocean fish. But instead of being distilled from fish oil, it is produced in enclosed culture systems, on land, without any pollution. It is the only plant-based vegan source of both EPA and DHA omega-3 made in the USA.

Fish oil supplements are considered safe only after being decontaminated. “No fish are involved in the production of Pure-One,” said Scott Doughman, Ph.D., president and chief scientist at Source Omega. “There is no seawater contact, no pollution, no impurities in the growing process.”

This purity is especially valuable now. The massive oil spill in the Gulf of Mexico not only adds petroleum to the sea water, but the chemical dispersants used to fight oil spills may cause equal contamination. These concerns are now added to long-standing concern about mercury pollution, which are as critical as ever.

A study published in June 2010 in Nature Geoscience demonstrates that methyl-mercury pollution lasts longer in oceans than in fresh water because of the sea salt. Mercury interferes with the brain and nervous system. The impact of chemicals from the oil spill is not yet known.

These concerns are absent from Pure One™. Because Pure One™ comes straight from algae rather than from fish, said Dr. Doughman, it meets the standard for infant formula. It is free of allergens, hexane, dye, and all toxins. Even kosher certification will be offered for Pure One™ in the near future, he said.

“This makes the oil good for those with sensitive digestion, diabetics, and the very young and the very old,” he said.

Pure-One™ is safe and effective, stable and sustainable. No species of fish are depleted in its production. Because it comes from the same source, Pure One™ algae oil has the same omega-3s as fish oil, but with a ratio that matches the composition of the human body. Research shows that it has positive effects on both heart and brain health, without the risk.

Source-Omega is located near the Research Triangle Park and was founded in 2007 for specializing in the manufacturing, branding, and globalization of algae oil nutritional products as an exclusive distributor of the brand name Pure One™, Next Generation Plant Based Omega-3™ for their Omega-3 DHA Therapy™, for clinics offering triglyceride lowering plasma lipids management programs and for pregnancy, nursing and family care. Dr. Scott Doughman, Ph.D. Phone: +19193605275, Web: www.PureOne-DHA.com and www.Source-Omega.com.


Pure One™ Algae Oil Champion Endorsement: Source-Omega Teams-Up with the Iron-Doc™ March, 2010

The Iron-Doc™ is a “well oiled machine” and Pure One™ algae oil omega-3s may have something to do with that. The Iron-Doc™ is training for competitions held around the world. Pure One™ producer Source-Omega sponsors the Iron-Doc™ to help give him a pure, sustainable advantage.

Chapel Hill, NC, March 29, 2010 --(PR.com)-- What’s faster than the Iron-Doc™? Maybe the Iron-Doc™ after 3-months of taking the new omega-3 algae oil, Pure One™ (patent pending). Pure One’s bottle says “Balanced to match your body’s omega-3 needs.”

For a triathlete, algae oil omega-3s provide a powerful oil supplement loved by the Doctor himself. He’s Pro-Athlete, Dr. Alex McDonald, M.D., Timex™ Multisport Team, Iron-Man™ Triathlon Champion and Medical Doctor. He’s a Doctor and the Iron-Doc™, in one person. His insight into fitness gives Pure One™ scientists feedback so that other athletes or fitness beginners can get the omega-3 benefits of the Pure One algae oil also.

“Last week I rode 378 miles, ran 48 miles and swam 11 miles! Pure One helps decrease inflammation in an athlete's body to let them train harder, faster and stronger, more consistently,” said the Iron-Doc™.

The Iron-Doc™ gets his omega-3s from algae oil for both DHA and EPA in an exclusive “metabolic ratio” only available from Pure One™. Getting more omega-3s is considered one of the best first steps to getting healthy. Dr McDonald’s omega-3 choice is Pure One™ algae oil, not fish oil.

Could algae oil be the best new source of omega-3 for athletes in all three sports, swimming, biking and running? Pure One™ scientists are hoping to find out more. “As for dosing, it is going well, 2 Pure One™ every morning and 2 after the last workout of the day. My training has been going very well. I had my first 110 mile bike ride of the season yesterday. It helps keep my body moving at peak performance.” – The Iron-Doc™ in a Pure One™ field report.

Now you can get algae oil to replace fish oil, dose for dose, without the fish smell or taste, without even the fish. The Pure One™ label talks about the actual plant based origins of all omega-3s. It says Pure One™ oil comes from the source, from algae oil, from where fish get their own “good” fats from, known as the omega-3s DHA and EPA, abundant in Pure One™.

About Source-Omega, LLC, Chapel Hill North Carolina, USA: Source-Omega is located near the Research Triangle Park, was founded by Dr. Scott Doughman in 2007, for specializing in the manufacturing, branding, and globalization of algae oil nutritional products as an exclusive distributor of the brand name Pure One™, The Next Generation Plant Based Omega-3™ for their Omega-3 DHA Therapy™, for clinics offering triglyceride lowering plasma lipids management programs and for pregnancy, nursing and family care. Dr. Scott Doughman, Ph.D. Phone: +19193605275, Web: www.source-omega.com.


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