Source-Omega (www.source-omega.com) today asserts the newest DHA omega-3 structure-function claim filed with the FDA to demonstrate how their exclusive product, SOURCE OIL® - Water Extracted Chromista Oil - best supports mitochondrial health and maintenance. SOURCE OIL is the first and only 50% DHA algae oil that is also the first and only water extracted algae oil offering the highest quality, purity and potency.

Based on emerging and qualified peer-reviewed research, independent study demonstrates that DHA is the only omega-3 used to make mitochondrial cardiolipin, but only when sufficient DHA intake levels are maintained over time.

Source-Omega's own publication reviews support 1200 mg DHA per day for 90 days as an average ideal intake level. Accretion is the act of building-up stores or reserves in the form of higher DHA levels over time, yet accretion is naturally limited to an average ideal level of about 8% total omega-3 membrane composition, thus posing no risk of overdose or side effects. Most people persist at about 4% total omega-3 membrane levels and have very little, if any, DHA in their mitochondrial cardiolipin.

Dr Scott Doughman, PhD, the Founder and Chief Scientific Officer of Source-Omega said, "The summary of 16 clinical studies using algae DHA proves tissue accretion therapy is effective and supports longevity. By using an average 1200mg DHA per day, within the range of 700 mg DHA to 1500 mg DHA per day, a person will double total omega-3s in their red blood cells in 90 days and in all cells within 12 months. But now we observe studies with similar intake levels that support DHA accretion in mitochondrial cardiolipin within the same time periods."

What is mitochondrial cardiolipin? Cardiolipin is a lipid complex that can only be made from certain fatty acids. Cardiolipin is a novel phospholipid made only in the mitochondria, which are the sole power factories for our body and cells.

Cardiolipin functions as a proton trap giving ATP synthase the juice needed to enhance electron transfer and reduce electron leakage. Cardiolipin also participates in a structural scaffold essential for the distinctive shape of mitochondrial cristae.

DHA is the only omega-3 that can be used to make this novel lipid, but only when DHA is consistently available in the diet at high enough levels. DHA is thought to also have electroconductive properties adding to its many uses in the human body, brain, eyes and heart.

"We claim SOURCE OIL DHA uses for providing the definitive omega-3 used by the mitochondria to form cardiolipin," said Dr Doughman

About Structure-Function Claims
What is a permitted structure-function statement? The FDA (www.fda.gov) states that "Dietary supplement labels or labeling may bear statements that describe the role of a nutrient or dietary ingredient intended to affect the structure or function in humans or that characterize the documented mechanism by which a nutrient or dietary ingredient acts to maintain such structure or function, provided that such statements are not disease claims."

Claims and general substantiations for the DHA brand SOURCE OIL are that it is an ingredient used in consumer finished products. All labels and labeling associated with SOURCE OIL contains the following statement: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The Source-Omega company has previously defined uses for DHA-rich algae oil in the the structure-function and formation of very low-density lipoproteins (VLDL) in the liver as the first act of DHA in the body, before it is deposited into cell membranes phospholipids and the mitochondria.

Their earlier work on VLDL biology demonstrated how precious DHA is in the liver, describing how the liver uses DHA selectively to move dietary fat and to transport it efficiently. The mechanisms described imply that DHA functions directly in maintaining normal plasma triglycerides levels and normal fatty liver levels.

About Source-Omega
Source-Omega, LLC is the leading Chromista algae oil innovations company since 2007 serving the public health using a unique water extraction process, lowering prices and improving quality. Preformed DHA has also been defined in Source-Omega's publications to be safe and effective for adults at 1200 mg DHA/day. The company defined 1200 mg DHA/day as a best practice for adults and showed how the liver can rapidly make EPA from DHA in just the right amounts (Doughman et al., 2013).

"Demand driven R&D proved to us that this oil was the best emulsifier of CBD oil preparations, from raw CBD oil to pure CBD isolate, achieving a 33% CBD concentrate at room temperature and a 50% CBD concentrate at only 45 degrees Celcius as stable, clear, fully emulsified solutions. The length and unsaturation of the lipids in our oil may be the most powerful natural oil emulsifier of CBD powders and pastes," said Scott Doughman, PhD, Chief Scientific Officer, CEO and Founder of Source-Omega, LLC.

Doughman said recent events foretell of the "the word getting out" and "boom demand" for the Chromista oil DHA. He disclosed 3rd party product developers are reaching the same astonishing conclusions about CBD emulsification with the DHA oil, stating that solid CBD decarboxylated oil concentrates in 1 gram "chunks" will dissolve, i.e. fully emulsify, into the Chromista oil simply by sitting overnight without heating, sonicating or mixing.

The premium DHA oil contains an average chain-length of 20 carbons, whereas olive oil's average chain-length is about 18 carbons, coconut oil's average is about 16 carbons and medium chain triglyceride (MCT) oil's average is about 10 carbons.

DHA in fish oil and krill oil comes from algae oil in the food chain. DHA is commonly used in food supplements because DHA is the most abundant omega-3 in the human body, brain and organs by ten-fold, with a maximum ratio of 97% DHA in the brain.

Recent interest in DHA has focused on two new endogenous wellness pathways; a) DHA-cardiolipin structure and function in the mitochondria, as DHA is the only omega-3 used by mitochondrial cardiolipin and only when DHA is sufficiently and consistently present in the diet, and b) DHA supplementation also appears to increase Synaptamide production in the brain.

In neurons, DHA can be directly converted into Synaptamide (Docosahexaenoylethanolamide), a structural analog of the endogenous cannabinoid receptor ligand anandamide, made from Arachidonic Acid. Synaptamide is synthesized from DHA in the brain, although it binds weakly to cannabinoid receptors, it independently stimulates growth, synaptogenesis and synaptic activity in developing hippocampal neurons at nano-molar concentrations. The term Synaptamide was coined to describe its activity and molecular similarity to anandamide.

Mason, OH, July 25, 2016 --(PR.com)-- Source-Omega today reiterated its active structure function claims in lipoprotein health and heart health and again asserted 'DHA Saves Lives' (1). Their claims statements are supported by the recent National Institutes of Health (NIH) article from June 12, 2016 (www.nih.gov) in Research Matters titled 'Omega-3s Linked with Lower Risk of Fatal Heart Attacks' (2), and the JAMA Internal Medicine research results published June 27, 2016 (3).

The authoritative 2016 references affirm fatal heart disease is a literal endpoint benefited by DHA omega-3s and the other shorter forms of omega-3 fatty acids when consumed at elevated dietary intake levels over time.

Source-Omega LLC is developer of Class 1 branded ingredient SOURCE OIL®, Chromista oil water extracted Schizochytrium sp. algae oil. The company maintains public health advocacy and scholarly publications in support of the DHA ratio in human heart tissue, which is 90 percent of all omega-3 fatty acids in the heart.

"DHA levels are ten-fold higher than any other omega-3 fatty acid in the human body. Individual omega-3 status is therefore based mostly on DHA levels, either consumed directly or derived from all other forms of omega-3s in the diet. Higher individual omega-3 status is linked to lower individual fatality by heart attack. So even if the world has not been able to stop all heart attacks, there is now specific evidence that shows a dietary buffer could be occurring with higher omega-3 intakes. The more omega-3 fats in the diet, the more DHA is produced and also stored in the body. Building up DHA is based on how much total omega-3s are in the diet. Clearly, it's more likely that one will survive an otherwise fatal heart attack. That is what the data says. We suggest DHA is the one lipid marker that may become more widely used as a standardized heart health indicator. It certainly can mean a statement like 'DHA saves lives' is scientifically qualified," said Dr Scott Doughman, PhD, CSO and CEO of Source-Omega, LLC.

About Source Omega
Source-Omega (http://www.source-omega.com) is the leading Chromista oil innovations company since 2007 serving health by offering a unique water extraction process in algae oil, lowering prices and improving quality. Preformed DHA has also been defined in Source-Omega's publications to be safe and effective for adults at 1200 mg DHA/day for lowering triglycerides (1).

References:
1) Scott. D. Doughman, Ph.D. et al., 2013; High DHA dosage from algae oil improves postprandial hypertriglyceridemia and is safe for type-2 diabetics. Int J Diabetes Dev Ctries (DOI 10.1007/s13410-013-0125-3).
2) Carol Torgan, Ph.D. June 12, 2016; Omega-3s Linked with Lower Risk of Fatal Heart Attacks (https://www.nih.gov/news-events/nih-research-matters/omega-3s-linked-lower-risk-fatal-heart-attacks).
3) Liana C. Del Gobbo, Ph.D. et al., Published online June 27, 2016; ?-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease Pooling Project of 19 Cohort Studies. JAMA Internal Medicine.

[by Scott Doughman, PhD, et al., All Copyrights Reserved] 

ABSTRACT FOR CONFERENCE TALK: 
With respect to algae oils, we consider the word "sustainability" in current food and fuel models. Overviews discussed are intended as general contexts for 1) the planet, for 2) finished oils, and for 3) growing new innovations. Part of the discussion considers trophic (nutrient) classifications. Heterotrophic algae systems may be defined as carbon-carbon bond consumers. Autotrophic algae systems may be defined as carbon-carbon bond producers, but are also consumers of their self-made carbon-carbon bonds to produce oil. All other organisms are also carbon consumers. Efficiency models for algae oils are also based on systems theory, but isolated data may suggest theoretical systems that need further proven. Because algae are inherently part of a "food chain" or an "economy" of scale, algae sciences increasingly have discovered paradigms for primary roles for algae in the discussion of "sustainability". New technologies for biomass, waste mitigation, and food and feed products require direct consumers over passive applications, such as fertilizer, due to the difference between direct and indirect consumption, especially with respect to the sustainability of water usage to produce oils. We suggest identification of a proven oil product and the direct consumer first be established in a stable system of production and consumption of materials prior to the ability to discuss sustainability criteria. The discussion applies to both heterotrophic algae systems and autotrophic algae systems. The source of the carbon is not relevant to our equation for carbon-carbon bond flow as a measure of sustainability with respect to oil, unless further qualified. We conclude algae oil sustainability is fundamentally based on a controlled measure of carbon-carbon bond flow compared to the direct use of the target oil product for food or fuel. 

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